Dan He, Ph.D

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Title

Associate Chief Technician

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Research Interests

She is proficient in the traditional histological techniques including HE staining, frozen section, cell culture, and immunohistochemistry. Recent research focuses on molecular diagnostic techniques which providing more evidence in the diagnosis and targeted therapy of tumors in clinical practice. FISH assay and PCR are applied to detect gene amplification, gene deletion, translocation and mutation for diagnosis?and?differential?diagnosis?in various cancers.

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Education and Experience

2016-now Associate Chief Technician, Department of Pathology, the third Affiliated Hospital, Sun Yat-Sen University

2008-2011 Ph.D, Sun Yat-Sen university

2007-2015 Technologist-in-charge, Department of Pathology, the third Affiliated Hospital, Sun Yat-Sen University?

2002-2005 Master of Midicine, Sun Yat-Sen University of medical sciences

1999-2006 Technician，Department of Pathology, the third Affiliated Hospital, Sun Yat-Sen University

1994-1999 Bachelor of Midicine, West China University of Medical Sciences

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Publications

1.He D1,?Zhang YW,?Zhang NN,?Zhou L,?Chen JN,?Jiang Y,?Shao CK. Aberrant gene promoter methylation of p16, FHIT, CRBP1, WWOX, and DLC-1 in Epstein-Barr virus-associated gastric carcinomas. Med Oncol.?2015 Apr;32(4):92. doi: 10.1007/s12032-015-0525-y. Epub 2015 Feb 27.

2.He D1,?Xiao L,?Chen JN,?Liang Q,?Shao CK Correlation of Fas/FasL expression to cell apoptosis in Epstein-Barr virus-associated gastric carcinoma. Chin J Cancer.?2010 Mar;29(3):283-7. ?

3.Chen JN, He D, Tang F, Shao CK. Epstein-Barr virus-associated gastric carcinoma: a newly defined entity . J Clin Gastroenterol. 2012 Apr;46(4):262-71.

4.Jin Y, Li JP, He D, Tang LY, Zee CS, Guo SZ, Zhou J, Chen JN, Shao CK . Clinical significance of human telomerase RNA gene (hTERC) amplification in cervical squamous cell lesions detected by fluorescence in situ hybridization. Asian Pac J Cancer Prev. 2011;12(5):1167-71

5.Chen JN, Ding YG, Feng ZY, Li HG, He D, Du H, Wu B, Shao CK Association of distinctive Epstein-Barr virus variants with gastric carcinoma in Guangzhou, southern China. J Med Virol. 2010 Apr;82(4):658-67.

6.Lan MX1,?Lan SZ,?Cheng ZF,?Dan H,?Qiong LH.Suppression of EBNA1 expression inhibits growth of?EBV-positive NK/T cell lymphoma cells Cancer Biol Ther.?2008 Oct;7(10):1602-6.??

7.Xiang-Lan M1,?Zu-Lan S,?Dan H,?Bi-Hong S,?Ya-Qin P,?Han-Liang L. Skp2/p27 expression profile is correlated with Epstein-Barr virus status in extranodal nasal-type natural killer cell lymphoma. Transl Res.?2008 Jun;151(6):303-8. doi: 10.1016/j.trsl.2008.04.004. Epub 2008 May 15.

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Contact

Department of Pathology

The?Third?Affiliated?Hospital,?Sun?Yat-sen?University

No. 600 Tianhe Road,?Guangzhou?510630,?China

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