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Titles
Associate Professor of?Hepatobiliary Surgery Department
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Research Interests
Surgical treatment of liver cancer
Surgical treatment of portal hypertension
Surgical treatment of hepatic, biliary, pancreatic and splenic diseases
The pathogenesis of hepatocellular carcinoma
He has been engaged in clinical and basic research work of primary liver cancer for many years. He accumulated rich clinical experience in surgery treatment and radiofrequency ablation of liver cancer. Over the years, he was involved in the MSC (mesenchymal stem cell) treatment for liver fibrosis and got the National Science Foundation for Young Scholars of China?in 2010.
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Education and Experience
Work Experience
2000.12-2005.12 ?Resident, General Surgery, The third affiliated hospital of Sun Yat-Sen University
2005.12-2010.11: Visiting staff, General Surgery, The third affiliated hospital of Sun Yat-Sen University
2010.12-now: associate senior doctor, Hepatobiliary Surgery Department, The third affiliated hospital of Sun Yat-Sen University
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Certifications
2005.09-2008.07: Doctor Degree, Surgery, Sun Yat-sen University
· 2000.0 Master Degree, Surgery, Sun Yat-sen University
1995.09-2000.07: Bachelor degree, Clinical medicine, Sun Yat-sen University
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Honors and Awards
1. 2010 National Science Foundation for Young Scholars of China
2. 2011 Natural Science Foundation of Guangdong Province
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Publications
1?Lin Nan, Hu Kupeng, Chen Si，Xie S, Tang Z, Lin Jizong, Xu Ruiyun*. Nerve growth factor-mediated paracrine regulation of hepatic stellate cells by multipotent mesenchymal stromal cells. Life Sci, 85(7-8): 291-5. 2009.（IF：2.527）.
2 Lin Nan,?Chen S, Pan W, Xu L, Hu K,?Xu Ruiyun*. NP603, a novel and potent inhibitor of FGFR1 tyrosine kinase, inhibits hepatic stellate cell proliferation and ameliorates hepatic fibrosis in rats. Am J Physiol Cell Physiol. 301(2): C469-77. 2011.?(IF:3.536)
3?Lin Nan,?Tang Z, Deng M, Zhong Y, Lin Jizong,Yang X, Xiang P, Xu Ruiyun. Hedgehog-mediated paracrine interaction between hepatic stellate cells and marrow-derived mesenchymal stem cells. Biochem Biophys Res Commun, 372(1):260-265.?2008（IF：2.484）
4?Lin Nan,?LinJizong，Liu bo，Pan weidong，chen si, Xu Ruiyun*?Differentiation of bone marrow-derived mesenchymal stem cells into hepatocyte-like cells in an alginate scaffold . Cell proliferation 43.427-434. 2010（IF：2.527）
5 Chen S, Xu L,?Lin Nan, Pan W, Hu K, Xu Ruiyun*?Activation of Notch1 signaling by marrow-derived mesenchymal stem cells through cell-cell contact inhibits proliferation of hepatic stellate cells. Life Sci. 89(25-26): 975-81.?2011.（IF：2.527）
6 Zhong Yuesi, Lin Nan，?Deng M, Zhang F, Tang Z, Xu Ruiyun*.?Deficient proliferation of bone marrow-derived mesenchymal stem cells in patients with chronic hepatitis B viral infections and cirrhosis of the liver. Dig Dis Sci, 55(2): 438-45. 2010（IF：2.117）
7 Lin Nan（Liu Bo, Xu Ruiyun, Deng Meihai Splenectomy with endoscopic variceal ligation is superior to sple-centomy with pericardial devascularization in treatment of portal hypertension. World Jourmal of Gastroenterology ,12(45):7375-7379.?2006（IF：2.471）
8?Nan lin, Xu linan, Xu jianglian, Human bone marrow mesenchymal stem cells over-exprssing α-melanocyte-stimulating hormone gene reverses carbon tetrachloride induced liver fibrosis in mice?. Hepatology.?56(4, suppl):777A (Abstract)?2012（IF：11.665）
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Contact
Department of Hepatobiliary Surgery, Third Affiliated Hospital of Sun Yat-Sen University
NO.600 TianHe road, Guangzhou city, 510630, Guangdong province, China
Email:drdmh@medmail.com.cn
Fax: 86-20-85253178.
Appointment Phone: 1331881889
